Equine Infectious Anemia Virus from Infected Horse Serum

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Equine infectious anemia virus from infected horse serum.

Equine infectious anemia virus was purified from infected horse serum samples. Electron microscope observation on negatively stained preparations of purified virus showed roughly spherical particles sized between 100 and 200 nm in diameter. In disrupted particles, an envelope was visible but no internal structure could be resolved. Since the purified virus fraction had a strong antigenic activi...

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The amount and distribution of viral DNA were established in a horse acutely infected with the Wyoming strain of equine infectious anemia virus (EIAV). The highest concentration of viral DNA were found in the liver, lymph nodes, bone marrow, and spleen. The kidney, choroid plexus, and peripheral blood leukocytes also contained viral DNA, but at a lower level. It is estimated that at day 16 post...

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Characterization of an equine infectious anemia antigen extracted from infected horse spleen tissue.

The spleens of horses infected with equine infectious anemia contain an antigen that is useful for a diagnostic immunodiffusion test. This antigen was extracted from the spleen by homogenization of the tissue, centrifugation, and precipitation from the supernatant fluid at 50% saturation with (NH(4))(2)SO(4). The antigen was purified by subjecting it to two cycles of electrophoresis in a contin...

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Demonstration of antigenic identity between purified equine infectious anemia virus and an antigen extracted from infected horse spleen.

Antigenic relationship between purified equine infectious anemia (EIA) virus and spleen-derived antigen from EIA-infected horses was examined by immunodiffusion. Identical antigenicity of these two antigens has been proven because precipitation lines formed between the two antigens and EIA antiserum connected with each other. The results indicate that the antigenic substance derived from infect...

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Equine infectious anemia virus in China

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1974

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.10.3.667-668.1974